Micky van de Ven Brace Ends Everton's Run at Brand New Stadium
The Dutch defender emerged as the first defender to score two goals in a English top-flight match for Tottenham since Jan Vertonghen in spring 2013.
Match summary
Micky Van de Ven nods home twice in opening period
Everton's defender has equalizer ruled after video check
Pape Matar Sarr nets third in dying moments
The defeat is Everton's initial at Hill Dickinson Stadium
The Tottenham defender scored twice as Spurs prolonged their winning streak in away games in the Premier League and delivered Everton their initial loss at their new home.
Everton were unbeaten in their last five matches at their new ground at the dockside location, having left their historic home behind after more than a century at the conclusion of the previous campaign.
But Tottenham's leader Van de Ven struck on two occasions from corners in the first half to put their strong form at jeopardy, and they were failed to turn it around before the midfielder - set up by ex-Everton forward Richarlison - headed home a third to put the game to bed.
The Everton defender believed he had equalized the tally a short while after the defender's opener, glancing a powerful header past Guglielmo Vicario from an Everton corner.
The Portuguese striker, in the meantime, failed to convert a number of opportunities, while Vicario made a series of fine stops to ensure the London club went five away games unbeaten in the Premier League.
But the video assistant referee stepped in, instructing the match official to check the score on the pitchside monitor and the official decided that the winger and Iliman Ndiaye were in an illegal position and had interfered with the Spurs keeper.
The win elevates Thomas Frank's team into third place in the division, five points off local foes and leaders Arsenal.
Everton stay in 14th position and sit half a dozen points clear of the drop zone.
Spurs breakdown: Van de Ven excels in duties at each end of pitch
After a uninspiring weekday performance in the Champions League against Monaco, where they managed a only two shots on target, Frank opted for the French striker up front instead of former Toffees player the Brazilian.
The summer signing was failed to make much of an impact before being replaced for Richarlison after 60 minutes on the field, but it emerged he proved unnecessary in the final outcome.
Defender the Dutchman converted into an offensive threat to be feared.
Spurs' first goal came from a well-worked corner routine, with Rodrigo Bentancur heading the ball back across the six-yard box for an free the defender to head home.
And the captain - stepping up as captain in the Argentine's unavailability - added his next goal in first-half stoppage time as he rose above Jordan Pickford to nod in.
Van de Ven was just as impressive in defence, combining well with Kevin Danso as the duo handled superbly with the numerous deliveries sent their way by the opposition.
Toffees breakdown: Everton lacking finishing touch
Everton's new home had been a happy hunting ground, but it appears the novelty may have worn off somewhat and fans flocked to the exits after the midfielder's third for Tottenham.
The break in Everton's winning streak at home won't be a major concern for David Moyes, but their attacking woes are.
The forward and the other striker - the Toffees' two established strikers - had scored only a single goal between them before Sunday's match.
And they were failed to contribute to that miserable record on a wet and gloomy night on in Liverpool.
The striker's performance was epitomized when he chose to bicycle-kick a golden opportunity from close range, even with having room and time to reposition for a more conventional shot that would have challenged Vicario.
Barry, too, was unable to make an impact after replacing the starter in the 65th minute.
It wasn't for a shortage of opportunity. Most of the home side's offensive moves came through the winger and the forward, who tirelessly whipped threatening balls into the Tottenham penalty area.
What next for these two sides?
Everton: Moyes' men travel to the Stadium of Light in the top flight on early November at 8 PM.
Tottenham: The London club travel to St James' Park on Wednesday, 29 October for their next round League Cup tie against Newcastle.